O termo “cara de Ozempic”, em inglês, “Ozempic face”, tem sido usado na internet nos últimos meses para se referir a um possível reflexo do uso desse medicamento, que deixaria o rosto com aspecto "murcho e caído". Ao jornal The New York Times, uma paciente chegou a relatar que, após tomá-lo, seu corpo "parecia ótimo”, mas seu “rosto aparentava estar exausto e velho”.
No TikTok, usuários já publicaram diversos vídeos mostrando suas experiências, sob a hashtag #ozempicface. Para entender como funciona o medicamento, Donna entrevista a endocrinologista do Hospital Mãe de Deus Melissa Barcellos Azevedo, sócia proprietária da Haux Clinic POA.
Primeiro, é preciso saber que o Ozempic tem como princípio ativo a semaglutida (em dosagem de até 1mg) e está autorizado no Brasil para uso contra diabetes tipo 2, mas que também tem sido usado, de forma off label (uso diferente daquele descrito em bula) para tratar a obesidade. É uma medicação injetável, em formato de caneta, que provoca uma perda de peso intensa em um pequeno intervalo de tempo em muitos casos.
No início deste mês, a fabricante, a farmacêutica Novo Nordisk, divulgou comunicado em que diz que “a companhia não endossa ou apoia a promoção de informações de caráter off label, ou seja, em desacordo com a bula de seus produtos”.
Para uso específico no tratamento da obesidade, a empresa criou uma nova solução, com dosagem maior de semaglutida (de até 2,4mg), chamada Wegovy. Esse medicamento foi aprovado em janeiro deste ano pela Agência Nacional de Vigilância Sanitária (Anvisa), mas ainda não tem data definida para ser disponibilizado nas farmácias brasileiras.
— Grande parte dos pacientes diabéticos tem excesso de peso. Portanto, o tratamento também tem como objetivo principal essa redução. Só que, devido à grande efetividade da medicação nesses casos, aram a estudá-la também para controle da obesidade em pacientes não-diabéticos. A doença é tão grave e tão potencialmente relacionada ao aumento de morbimortalidade, que a dose para controle (2,4mg) é mais alta do que a própria indicação para diabetes (1mg) — observa Melissa.
Na internet, os medicamentos tem ganhado popularidade à medida em que celebridades americanas e brasileiras, como o CEO da Tesla, Elon Musk, a comediante Chelsea Handler e a cantora Jojo Todynho, têm vindo a público revelar que usaram ou usam esses fármacos para perder gordura. Mas o que ocorre no rosto">
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